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Vohwinkel’s syndrome differs from Mal de- Meleda of the an autosomal dominating inheritance and mutations recognized to your GJB2 gene, hence encodes the fresh new pit junction connexin26 . SLURP-step 1 is one of the Ly-6/uPAR receptor superfamily and you may released necessary protein, which happen to be proven to take part in rule transduction, protected telephone activation, and you will cellular adhesion. SLURP-step 1 reveals a leading level of structural resemblance for the about three fingertips theme regarding serpent neurotoxins, which suggests the communications towards neuronal acetylcholine receptors. SLURP-step 1 potentiates individual leader seven nicotinic acetylcholine receptors contained in keratinocytes . Czytaj więcej